Since the Summer of 2014, I have been working with my faculty advisor, Dr. Nancy Krucher, conducing in breast cancer research with a specific focus on the tumor suppressor Retinoblastoma protein and its phosphorylation sites. More importantly, our lab's focus was how dephosphorylation of the Rb protein through a process called PNUTS knockdown contributes to apoptosis, invasion, and the EMT in breast cancer. During the Summer of 2014, I was a part of the Summer Undergrad Student-Faculty Research Program working on apoptosis in breast cancer cells growing in 3-D tumors. I was later enrolled in the 2014-2015 President & Provost Student-Faculty Research to continuing work with growing breast cancer cells in a 3-D environment, specifically working with a not very invasive breast cancer cell line: MCF7s. After completion of this project, my focus had shifted onto a new topic: invasion and the epithelial-to-mesenchymal transition. Lastly, I was working with an in-vitro model invasion assay to assess the ability of a highly invasive fibrosarcoma cell line, HT-1080's, to invade a representative extracellular matrix barrier after PNUTS depletion from the Rb protein.